Connective Tissue Disorders

1.3.1 Discuss antigen relationships in connective tissue diseases.

1.3.2 Systemic Lupus Erythematosus: Criteria for diagnosis of SLE. What are common head and neck manifestations of Lupus and their treatment?

1.3.3 Rheumatoid Arthritis: Head and Neck manifestations, diagnosis and treatment.

1.3.4 Sjogren’s Syndrome-primary vs. secondary forms. What is Mikulicz’s disease? Review the diagnosis, H&N manifestations and treatment of Sjogren’s.

1.3.5 Scleroderma-Describe pathophysiology, H&N manifestations, and treatment. How is it related to CREST?

1.3.6 Polymyositis and dermatomyositis: What are they and how do they differ? Diagnosis, H&N manifestations and treatment?

1.3.7 Relapsing polychondritis. How do these patients present? What are common H&N manifestations? How is this disorder diagnosed and treated?

1.3.8 Discuss otorhinolaryngologic manifestations (including otologic and airway findings) of Wegener’s Granulomatosis including their diagnosis and treatment. What other organ systems are affected by Wegner's?

http://portal.entnet.org/images/COCLIA/2011-2012%20updates/COCLIA%20Media/Connective%20Tissue%20Disorders/ConnectiveTissueDisorders-Q8-081118_074.jpg

O'Devaney K, Ferlito A, Hunter BC, Devaney SL, Rinaldo A. Wegener's granulomatosis of the head and neck. Ann Otol Rhinol Laryngol. 1998 May;107(5 Pt 1):439-4. Review. PMID:9596226

1.3.9 A 16 year old Asian male presents with recurrent aphthous ulcers. Could he have Bechet’s Disease? Discuss the manifestations of this disease and the treatment options.

1.3.10 Discuss the different types of cartilage and the common locations where each type is found. Relapsing polychondritis effects which kind of cartilage?