Nasopharyngeal Carcinoma

2.7.1 What are the risk factors for nasopharyngeal carcinoma (NPC)?

2.7.2 Describe the most common clinical presentation of NPC. 

http://portal.entnet.org/images/COCLIA/2011-2012%20updates/COCLIA%20Media/Nasopharyngeal%20Carcinoma/Nasopharyngeal%20Carcinoma-%20Q2-081118_170.jpg

2.7.3 What is the role of EBV in the etiology, detection, and surveillance for NPC?

2.7.4 Discuss the classification of NPC and significance of the different types.

2.7.5 Discuss the staging of NPC and different treatment modalities for each.

2.7.6 What are favorable prognostic factors?

2.7.7 What role do neck dissections play in the treatment of NPC?

2.7.8 What clinical and molecular markers distinguish sino-nasal undifferentiated carcinoma (SNUC) from esthesioneuroblastoma and melanoma? How are they treated?

2.7.9 A patient receives external radiotherapy for NPC and fails at the primary site. What are the salvage options? Results?

2.7.10 A 65-yr-old male develops diplopia, nasal obstruction, and hearing loss. Biopsy reveals NPC. The following images are his clinical exam and imaging. How can you explain the diplopia? 

http://portal.entnet.org/images/COCLIA/2011-2012%20updates/COCLIA%20Media/Nasopharyngeal%20Carcinoma/Nasopharyngeal%20Carcinoma-%20Q10-081118_169.jpg

2.7.11 Discuss the current treatment recommendations for NC according to stage. When would you add chemotherapy to the regimen? Which drugs?

2.7.12 What is the best diagnostic tool to evaluate for residual or recurrent disease?