Sensorineural Hearing Loss

3.13.1 Review the patterns of hearing loss in hereditary hearing impairment.

3.13.2 Discuss Connexin 26 mutations associated with non-syndromic hearing loss.

3.13.3 What are the infectious causes of congenital hearing loss?

3.13.4 Discuss presbycusis and Schuknecht classification.

3.13.5 What were the conclusions of Framingham study in age-related hearing loss?

3.13.6 You are called to the ER to see a pt with sudden sensorineural hearing loss. Discuss the work-up.

3.13.7 What is the natural history of sudden sensorineural hearing loss?

3.13.8 Describe the treatment for sudden sensorineural hearing loss. Is the addition of antivirals effective?

Tucci DL, Farmer JC Jr, Kitch RD, Witsell DL. Treatment of sudden sensorineural hearing loss with systemic steroids and valacyclovir. Otol Neurotol. 2002 May;23(3):301-8. PMID:11981385

Westerlaken BO, Stokroos RJ, Dhooge IJ, Wit HP, Albers FW. Treatment of idiopathic sudden sensorineural hearing loss with antiviral therapy: a prospective, randomized, double-blind clinical trial. Ann Otol Rhinol Laryngol. 2003 Nov;112(11):993-1000. PMID:14653370.

Stachler RJ, Chandrasekhar SS, Archer SM, et al. Clinical Practice Guideline: Sudden Hearing Loss. Otolaryngol Head Neck Surg. 2012 146: S1. DO~/images 10.1177/0194599812436449

3.13.9 Which drugs are known to be ototoxic? What is the mechanism of toxicity?

3.13.10 Discuss the pathogenesis and mechanism of noise induced hearing loss (NIHL).

3.13.11 Discuss OSHA regulation on noise exposure.

3.13.12 Review the calculation of hearing handicap and compensation.

3.13.13 What is the long-term efficacy of steroids vs. methotrexate in maintaining hearing improvement in patients with autoimmune inner ear disease?

Harris JP. et al. Treatment of corticosteroid-responsive autoimmune inner ear disease with methotrexate: a randomized controlled trial. JAMA. 2003 Oct 8;290(14):1875-83. PMID:14532316

3.13.14 What are the audiometric criteria for cochlear impantation?